IkB-beta Antibodies

Target Information

a protein of the NF-kappa-B inhibitor family. Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. Belongs to the NF-kappa-B inhibitor family. Expressed in all tissues examined. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

I-kappa-B-beta; I(Kappa)B(beta); IKapp; IkappaBbeta; IkB; IkB-B; IkB-beta; IKBB; Ikbb; MGC36057; NF-kappa-B inhibitor beta; NF-kappa-BIB; NFKB inhibitor beta; NFKBIB; Nfkbib; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; OTTMUSP00000018308; OTTMUSP00000018309; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9; TRIP9