MAP6 Antibodies

Target Information

Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B. Regulates KIF5A-mediated axonal cargo transport. Regulates axonal growth during neuron polarization. Belongs to the STOP family. Expressed in brain (at protein level). Expressed in spinal cord. Isoform 2 expression is up-regulated in the prefrontal cortex (Brodmann's area 46) of patients with schizophrenia (postmortem brain study). 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names