POSTN Antibodies

Target Information

Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX. Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers. 7 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

A630052E07Rik; AI747096; MGC119510; MGC119511; OSF; OSF-2; OSF2; Osf2; osteoblast specific factor 2 (fasciclin I-like); Osteoblast-specific factor 2; PDLPOSTN; peri; periodontal ligament-specific periostin; Periostin; periostin isoform thy2; periostin isoform thy4; periostin isoform thy6; periostin isoform thy8; periostin-like factor; periostin, osteoblast specific factor; PLF; PN; POSTN; Postn; RP11-412K4.1