CD80 Antibodies

Target Information

Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. (Microbial infection) Acts as a receptor for adenovirus subgroup B. Expressed on activated B-cells, macrophages and dendritic cells. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

Activation B7-1 antigen; B-lymphocyte activation antigen B7; B7; B7 protein; B7-1; B7.1; B71; BB1; Cd28; Cd28l; CD28LG; CD28LG1; CD80; Cd80; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly-5; Ly-53; Ly5; Ly53; MIC17; T-lymphocyte activation antigen CD80; TSA1