GABARAPL1 Antibodies

Target Information

Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Belongs to the ATG8 family. Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine. In the brain, expression is particularly intense in motoneurons in the embryo and in neurons involved in somatomotor and neuroendocrine functions in the adult, particularly in the substantia nigra pars compacta. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

APG8-LIKE; APG8L; ATG8; ATG8B; ATG8L; Early estrogen-regulated protein; GABA type A receptor associated protein like 1; GABA(A) receptor-associated protein like 1; GABA(A) receptor-associated protein-like 1; GABARAPL1; Gamma-aminobutyric acid receptor-associated protein-like 1; GBRL1; GEC-1; GEC1; Glandular epithelial cell protein 1