Ig-beta Antibodies

Target Information

Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. B-cells. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

AGM6; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; B29; CD79B; CD79B antigen; CD79b antigen (immunoglobulin-associated beta); CD79b molecule; CD79b molecule, immunoglobulin-associated beta; Ig-beta; IGB; Immunoglobulin-associated B29 protein