IL6R Antibodies

Target Information

Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. Belongs to the type I cytokine receptor family. Type 3 subfamily. Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

CD126; CD126 antigen; gp80; HIES5; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL-6R; IL-6R 1; IL-6R subunit alpha; IL-6R-1; IL-6R-alpha; IL-6RA; IL6Q; IL6QTL; IL6R; Il6r; IL6RA; Il6ra; IL6RQ; interleukin 6 receptor; interleukin 6 receptor alpha subunit; interleukin 6 receptor, alpha; Interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991; MGC30256; sIL6R; Soluble interleukin-6 receptor subunit alpha