K10 Antibodies

Target Information

Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur. Belongs to the intermediate filament family. Seen in all suprabasal cell layers including stratum corneum. Expressed on the surface of lung cell lines (PubMed:19627498). Note: This description may include information from UniProtKB.

Alternate Names

56 kDa cytokeratin; BCIE; BIE; CK-10; CK10; cytokeratin 10; Cytokeratin-10; D130054E02Rik; EHK; epidermal keratin 10; intermediate filament protein; K10; K1C1; K1C10; keratin 10; keratin 10, type I; keratin complex 1, acidic, gene 10; Keratin-10; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 59 kDa; KPP; Krt-1.1; Krt-1.10; Krt1-1; Krt1-10; KRT10; Krt10; OTTMUSP00000005149; suprabasal cytokeratin 10