K14 Antibodies

Target Information

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. Belongs to the intermediate filament family. Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. Note: This description may include information from UniProtKB.

Alternate Names

AI626930; CK-14; CK14; cytokeratin 14; Cytokeratin-14; EBS3; EBS4; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; K1C14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin complex 1, acidic, gene 14; Keratin-14; Keratin, type I cytoskeletal 14; Krt-1.1; Krt-1.14; Krt1-1; Krt1-14; KRT14; Krt14; NFJ; OTTMUSP00000002389