LAMTOR4 Antibodies

Target Information

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Belongs to the LAMTOR4 family. Note: This description may include information from UniProtKB.

Alternate Names

C7orf59; LAMTOR4; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; late endosomal/lysosomal adaptor, MAPK and MTOR activator 4; LOC389541; LTOR4; Ragulator complex protein LAMTOR4; Ragulator complex protein LAMTOR4, N-terminally processed; UPF0539 protein C7orf59