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MLKL Antibodies

You can find the right MLKL antibody for your scientific research with our 9 antibodies developed in Mouse and Rabbit. These antibodies are validated for detecting MLKL in Human and Mouse samples using techniques like Western Blotting, Immunofluorescence (Immunocytochemistry), ELISA+, Immunoprecipitation and Simple Western™. Our MLKL antibodies have been cited in 716 publications and have 23 product images.

Target Information

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity. Binds to highly phosphorylated inositol phosphates such as inositolhexakisphosphate (InsP6) which is essential for its necroptotic function. Belongs to the protein kinase superfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

9130019I15Rik; FLJ34389; hMLKL; mixed lineage kinase domain like pseudokinase; mixed lineage kinase domain-like; Mixed lineage kinase domain-like protein; MLKL; Mlkl

MLKL Antibody Products

9 Products
Product #
Product Name
Applications
Reactivity
Clonality
1-9 of 9
Application Key:
WB - Western
IHC - Immunohistochemistry
IF - Immunofluorescence
F - Flow Cytometry
ChIP - Chromatin Immunoprecipitation
ELISA+ - ELISA and/or ELISA-like Assays
Species Cross-Reactivity Key:
H-Human M-Mouse R-Rat Hm-Hamster Mk-Monkey Vir-Virus Mi-Mink C-Chicken Dm-D. melanogaster X-Xenopus Z-Zebrafish B-Bovine Dg-Dog Pg-Pig Sc-S. cerevisiae Ce-C. elegans Hr-Horse GP-Guinea Pig Rab-Rabbit All-All Species Expected

Why CST

Cell Signaling Technology is trusted by the global scientific research community. Our highly cited antibodies offer unrivaled specificity and reproducibility. Learn more about why researchers choose CST:

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