NKRF Antibodies
Target Information
Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
ITBA4; NF-kappa-B-repressing factor; NFKB repressing factor; NFkB-repressing factor; NKRF; NRF; Protein ITBA4; Transcription factor NRFNKRF Antibody Products
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