PUMA Antibodies
Target Information
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis. Belongs to the Bcl-2 family. Ubiquitously expressed. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
BBC3; Bbc3; Bcl-2 binding component 3; Bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; BCL2 binding component 3; BH3-only; FLJ42994; JFY-1; JFY1; OTTMUSP00000025190; p53 up-regulated modulator of apoptosis; p53-upregulated modulator of apoptosis; PUMA; Puma; PUMA/JFY1PUMA Antibody Products
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