SHOC2 Antibodies

Target Information

Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. Belongs to the SHOC2 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

FLJ60412; KIAA0862; Leucine-rich repeat protein SHOC-2; NSLH1; Protein soc-2 homolog; Protein sur-8 homolog; SHOC2; SHOC2 leucine rich repeat scaffold protein; SIAA0862; SOC-2; soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); SOC2; suppressor of clear, C. elegans, homolog of; SUR-8; SUR8