TSPO Antibodies

Target Information

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. Belongs to the TspO/BZRP family. Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.

Alternate Names

benzodiazepine peripheral binding site; benzodiazepine receptor, peripheral; BPBS; BZRP; Bzrp; DBI; IBP; isoquinoline-binding protein; MBR; Mbr; mDRC; Mitochondrial benzodiazepine receptor; PBR; PBS; peripheral benzodiazepine receptor; Peripheral-type benzodiazepine receptor; pk18; PKBS; PTBR; RP3-526I14.4; Translocator protein; translocator protein (18kDa); TSPO; Tspo; Tspo1; TSPOA