Render Target: STATIC
Render Timestamp: 2024-09-13T10:59:42.393Z
Commit: 78210eeeea5b845c078d553d401bea8346e49321
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PDP - Template Name: Growth Factors and Cytokines
PDP - Template ID: *******9ad1159

Human FGF-6 Recombinant Protein #74782

    Product Information

    Storage

    Human FGF-6 Recombinant Protein is supplied as lyophilized material that is very stable at -20°C. It is recommended to reconstitute with sterile water at a concentration of 0.1 mg/mL which can be further diluted in aqueous solutions as needed. Addition of a carrier protein (0.1% HSA or BSA) is recommended for long-term storage.

    Once in solution, store at 4°C and use within 1 month, or store at -20ºC to -80ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles if storing reconstituted material at -20ºC to -80ºC.

    Product Description

    MW (kDa) 18.9
    Purity A greater than or equal to 95% purity was determined by SDS-PAGE.
    Endotoxin Endotoxin levels are less than or equal to 1 EU / 1 μg hFGF-6.
    Activity The bioactivity of recombinant hFGF-6 was determined in an NR6R-3T3 cell proliferation assay. The ED50 of each lot is less than or equal to 1 ng/mL.

    Source / Purification

    Recombinant human FGF-6 was expressed in E. coli and is supplied in a lyophilized form.

    Background

    FGF-6 is a member of the large and diverse fibroblast growth factor (FGF) family of peptide growth factors. FGF-6 binds to receptor FGFR4 and functions as a signaling molecule that is involved in many important processes (1,2). The mouse homolog of this gene exhibits predominantly in the myogenic lineage which suggests a role in muscle regeneration or differentiation (3,4). FGF-6 was able to transform NIH/3T3 cells and the resulting transformant formed a well-vascularized tumor in nude mice, thus suggesting an angiogenic property similar to some other members of the FGF family (4).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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