Human FGF-9 Recombinant Protein #54319
Product Information
Storage
Once in solution, store at 4°C and use within 1 month, or store at -20ºC to -80ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles if storing reconstituted material at -20ºC to -80ºC.
Product Description
| MW (kDa) | 23.4 |
| Purity | A greater than or equal to 95% purity was determined by SDS-PAGE. |
| Endotoxin | Endotoxin levels are less than or equal to 1 EU / 1 μg hFGF-9. |
| Activity | The bioactivity of recombinant hFGF-9 was determined in an NR6R-3T3 cell proliferation assay. The ED50 of each lot is less than or equal to 2 ng/ml. |
Source / Purification
Recombinant human FGF-9 was expressed in E. coli and is supplied in a lyophilized form.
Background
Fibroblast growth factor (FGF)-9 is a member of the larger FGF family of proteins that play key roles in development, cancer, and metabolism. Binding of FGF-9 to its receptor requires interaction with heparin and induces receptor dimerization, subsequent transphosphorylation, and downstream activation of Erk, Akt, and PLCγ pathways (1). FGF-9 is important for organ development and bone repair (2-4).
Limited Uses
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