Render Target: STATIC
Render Timestamp:
6/9/2026, 5:45:15 AM EDT
6/9/2026, 9:45:15 AM UTC
Commit: 33ae406c5df2bbc7a7d3c17605228fbeff8ea416
XML generation date: 2025-10-29 17:30:07.166
Product last modified at: 2025-12-21T22:56:08.783Z
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PDP - Template Name: Blocking Peptide
PDP - Template ID: *******6db2f4c

ATGL Blocking Peptide #1006

Inquiry Info. # 1006

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    Product Information

    Product Usage Information

    For immunohistochemistry, add twice the volume of peptide as volume of antibody used in 100 µl total volume. Incubate for a minimum of 30 minutes prior to adding the entire volume to the slide. Recommended antibody dilutions can be found on the relevant product data sheet.

    Storage

    Supplied in 20 mM potassium phosphate (pH 7.0), 50 mM NaCl, 0.1 mM EDTA, 1 mg/ml BSA and 5% glycerol. Store at –20°C.

    Product Description

    This peptide is used to block ATGL (30A4) Rabbit mAb #2439 reactivity in immunohistochemistry protocols.

    Quality Control

    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry. The peptide blocks ATGL (30A4) Rabbit mAb #2439 by immunohistochemistry.

    Background

    Triglycerides form an important energy store in many living organisms. Adipose tissue serves as the primary storage depot for triglycerides in mammals. Lipolytic enzymes mobilize triglycerides during periods of starvation to provide organisms with necessary energy. Hormone-sensitive lipase (HSL), the first identified lipolytic enzyme, hydrolyzes triglycerides in mammalian adipose tissues (1-3). Additional lipolytic enzymes, including adipose triglyceride lipase (ATGL), have also been discovered. The primary function of ATGL is to catalyze the hydrolysis of the first ester bond of lipid molecules. This enzyme may provide diglyceride substrates for HSL hydrolysis. ATGL is abundantly expressed in murine white and brown adipose tissue, and is highly substrate specific (4). ATGL was independently identified as desnutrin (5) and the TG-hydrolace inducible phospholipase-A2-ζ (6).
    For Research Use Only. Not for Use in Diagnostic Procedures.
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