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Commit: 33ae406c5df2bbc7a7d3c17605228fbeff8ea416
XML generation date: 2026-06-02 15:30:45.365
Product last modified at: 2026-06-03T07:01:18.382Z
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PDP - Template Name: Antibody Sampler Kit
PDP - Template ID: *******4a3ef3a
  1. Products /
  2. Primary Antibodies /
  3. AMPA Receptor (GluA) Antibody Sampler Kit

AMPA Receptor (GluA) Antibody Sampler Kit #8652

    Product Information

    Kit Usage Information

    Protocols

    Product Description

    The AMPA Receptor (GluA) Antibody Sampler Kit provides an economical means of evaluating the four subunits of AMPARs. The kit contains enough primary and secondary antibodies to perform two western blot experiments with each antibody.

    Background

    AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate, and NMDA (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are composed of four subunits (GluA1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity (1). In contrast to GluA2-containing AMPARs, AMPARs that lack GluA2 are permeable to calcium (2). Post-transcriptional modifications (alternative splicing, nuclear RNA editing) and post-translational modifications (glycosylation, phosphorylation) result in a very large number of permutations, fine-tuning the kinetic properties of AMPARs. Research studies have implicated activity changes in AMPARs in a variety of diseases including Alzheimer’s, amyotrophic lateral sclerosis (ALS), stroke, and epilepsy (1).

    Alternate Names

    AMPA; AMPAR; amparnmdar; GluR; Glut receptor; Glutamate receptor; Glutamate receptor ionotropic; GPCR; GRIA

    Database Links

    UniProt ID: P42261 , P42263 , P48058 , P42262


    Entrez-Gene Id: 2890 , 2892 , 2893 , 2891


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    For Research Use Only. Not for Use in Diagnostic Procedures.
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