ARID3B (F9T7Z) Rabbit Monoclonal Antibody #30089
- WB
- IP
Product Specifications
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 70 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
ARID3B is also a regulator of many cancer stem cell genes and has also been linked to cellular transformation and tumor progression (7-9). This protein is present in various tumor tissues; however, its expression and relevance to disease progression are context-dependent. For example, ARID3B expression has been linked to the progression of breast cancer, ovarian cancer, and malignant neuroblastoma (9-12). At the same time, its overexpression is associated with better prognosis in colorectal and breast cancer patients (13,14).
- Patsialou, A. et al. (2005) Nucleic Acids Res 33, 66-80.
- Kim, D. and Tucker, P.W. (2006) Mol Cell Biol 26, 2187-201.
- Kim, D. et al. (2007) J Biol Chem 282, 15768-77.
- Casanova, J.C. et al. (2011) Development 138, 1195-205.
- Takebe, A. et al. (2006) Dev Biol 293, 25-37.
- Pratama, E. et al. Biochem Biophys Res Commun 468, 248-54.
- Dausinas, P. et al. (2020) Gene 738, 144458.
- Cowden Dahl, K.D. et al. (2009) Neoplasia 11, 1208-15.
- Kobayashi, K. et al. (2006) Cancer Res 66, 8331-6.
- Joseph, S. et al. (2012) PLoS One 7, e42159.
- Akhavantabasi, S. et al. (2012) Cell Struct Funct 37, 27-38.
- Roy, L. et al. (2014) Oncotarget 5, 8355-66.
- Deutelmoser, H. et al. (2020) Int J Mol Sci 21, 8150. doi: 10.3390/ijms21218150.
- Zhang, J. et al. (2021) Aging (Albany NY) 13, 5621-5637.
Alternate Names
ARI3B; ARID domain-containing protein 3B; ARID3B; AT rich interactive domain 3B (BRIGHT- like); AT rich interactive domain 3B (BRIGHT-like); AT-rich interaction domain 3B; AT-rich interactive domain-containing protein 3B; BDP; Bright and dead ringer protein; Bright-like protein; DRIL2
Limited Uses
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