Render Target: STATIC
Render Timestamp: 2024-10-11T10:19:08.575Z
Commit: 56767fe525c928647c8401233a175d0d607d385d
XML generation date: 2024-05-10 22:35:38.043
Product last modified at: 2024-08-29T12:15:34.989Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77

CA 19-9 (C241:5:1:4) Mouse mAb #68030

Filter:
  • IHC

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa)
    Source/Isotype Mouse IgG1
    Application Key:
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    IHC Leica Bond 1:400 - 1:1600
    Immunohistochemistry (Paraffin) 1:800 - 1:3200

    Storage

    Supplied in PBS containing 1% BSA and 15 mM sodium azide. Stable for 6 months when stored at 4°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    CA 19-9 (C241:5:1:4) Mouse mAb recognizes endogenous levels of CA 19-9 protein. This antibody has minimal cross-reactivity (<1%) with sialyl lacto-N-tetraosylceramide. This antibody does not cross-react with Lewis A, Lewis B, or structurally-related substances.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with human colorectal adenocarcinoma Colo 205 cells.

    Background

    CA 19-9 specifically binds to the epitope of sialylated Lewis A carbohydrate structure, which is the functional ligand for E-selectin and is involved in the adhesion of cancer cells (1,2). The CA 19-9 antigen has been of clinical interest in detection, diagnosis, and management of cancers such as pancreatic and gastrointestinal carcinomas (3,4).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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