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Commit: 33ae406c5df2bbc7a7d3c17605228fbeff8ea416
XML generation date: 2026-06-03 05:09:44.367
Product last modified at: 2026-06-03T08:00:12.125Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
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Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

CD68 (D4B9C) Feline Chimeric Monoclonal Antibody #67816

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  • IHC

    Product Specifications

    REACTIVITY H Mk
    SENSITIVITY Endogenous
    MW (kDa)
    Source/Isotype Feline chimeric IgG1
    Application Key:
    • IHC-Immunohistochemistry 
    Species Cross-Reactivity Key:
    • H-Human 
    • Mk-Monkey 

    Product Information

    Product Description

    This Cell Signaling Technology® antibody retains the antigen-binding Fab regions of the original parent host sequence from which it is engineered. This antibody is expected to exhibit the same species cross-reactivity as CD68 (D4B9C) Rabbit Monoclonal Antibody #76437.

    Product Usage Information

    Application Dilution
    Immunohistochemistry (Paraffin) 1:50 - 1:200

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    CD68 (D4B9C) Feline Chimeric Monoclonal Antibody recognizes endogenous levels of total CD68 protein.

    Species Reactivity:

    Human, Monkey

    Source / Purification

    This recombinant chimeric antibody is engineered from CD68 (D4B9C) Rabbit Monoclonal Antibody #76437 according to animal-free protocols. The chimeric antibody retains its antigen-binding Fab regions from the original rabbit monoclonal antibody, but contains a feline-derived Fc domain. When multiplexing, Fc-directed rabbit secondaries are required to detect rabbit-host primary antibodies.

    The parent antibody, CD68 (D4B9C) Rabbit Monoclonal Antibody #76437, is produced by immunizing animals with recombinant human CD68 protein.

    Background

    CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).

    Alternate Names

    CD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1

    For Research Use Only. Not for Use in Diagnostic Procedures.
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