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EBNA1-binding protein 2 (F3W6K) Rabbit Monoclonal Antibody #85561

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  • WB

    Product Specifications

    REACTIVITY H M R
    SENSITIVITY Endogenous
    MW (kDa) 42
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    EBNA1-binding protein 2 (F3W6K) Rabbit Monoclonal Antibody recognizes endogenous levels of total EBNA1BP2 protein.

    Species Reactivity:

    Human, Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala239 of human EBNA1BP2 protein.

    Background

    Epstein-Barr virus (EBV) genomes persist in the proliferating cell nuclei as double-stranded circular DNA plasmids. The replication and segregation of EBV DNA requires a single viral protein, Epstein-Barr nuclear antigen 1 (EBNA1), in addition to cellular factors (1). The ability of EBNA1 to support long-term EBV DNA replication and episome maintenance in cells depends on its interaction with EBNA1-binding protein 2 (EBNA1BP2) (2). EBV infection has been closely linked to the development of various cancer types. EBNA1BP2 has been investigated as a prognostic biomarker for multiple tumor types in pan-cancer analysis (3).

    Alternate Names

    EBNA1 binding protein 2; EBNA1-binding protein 2; EBNA1BP2; EBP2; homolog of yeast EBNA1-binding protein; NOBP; nuclear FGF3 binding protein; Nucleolar protein p40; P40; Probable rRNA-processing protein EBP2

    For Research Use Only. Not for Use in Diagnostic Procedures.
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