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  1. Products /
  2. Primary Antibodies /
  3. IMP1 Antibody

IMP1 Antibody #2852

Filter:
  • WB

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 64
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    IMP1 Antibody detects endogenous levels of total IMP1 protein.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human IMP1 protein. Antibodies are purified by peptide affinity chromatography.

    Background

    Insulin-like growth factor-II mRNA-binding proteins (IMPs) belong to a family of zipcode-binding proteins (1,2). Three members of this family, IMP1, IMP2, and IMP3, have been identified (1,2). They contain two RNA recognition motifs, four K homology domains, and were found to function in mRNA localization, turnover, and translation control (1,2). Research studies have implicated these proteins in a variety of physiological and pathological processes, such as growth and development (3), testicular neoplasia (4), and melanocytic neoplasia (5).

    Alternate Names

    CRD-BP; CRDBP; IGF2BP; IGF2BP1; imp; imp-1; imp1; RNA transport; VICKZ; VICKZ1; ZBP; ZBP1; Zipcode

    Database Links

    UniProt ID: Q9NZI8


    Entrez-Gene Id: 10642


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    For Research Use Only. Not for Use in Diagnostic Procedures.
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