p15 INK4B Antibody #4822
- WB
- F
Inquiry Info. # 4822
Please see our recommended alternatives.
Product Specifications
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 15 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
- F-Flow Cytometry
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Flow Cytometry (Fixed/Permeabilized) | 1:25 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
The gene encoding p15 INK4B is often silenced by hypermethylation in acute myeloid leukemia and deleted in acute lymphocytic leukemia (6).
- Lukas, J. et al. (1996) Mol. Cell. Biol. 16, 6917-6925.
- Bai, F. et al. (2003) Mol. Cell. Biol. 23, 1269-1277.
- Noh, S.J. et al. (1999) Cancer Res. 59, 558-564.
- Guan, K.L. et al. (1994) Genes Dev. 8, 2939-2952.
- Hirai, H. et al. (1995) Mol. Cell. Biol. 15, 2672-2681.
- Drexler, H.G. (1998) Leukemia 12, 845-859.
Alternate Names
CDK inhibitory protein; CDK4B inhibitor; CDK4I; CDKN2B; CDN2B; cyclin dependent kinase inhibitor 2B; Cyclin-dependent kinase 4 inhibitor B; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinases 4 and 6 binding protein; INK4B; MTS-2; MTS2; Multiple tumor suppressor 2; p14_CDK inhibitor; p14_INK4B; p14-INK4b; P15; p15 CDK inhibitor; p15_INK4B; p15-INK4b; p15INK4B; TP15
Limited Uses
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