Phospho-Caspase-9 (Thr125) Antibody #2226
Inquiry Info. # 2226
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Product Specifications
| REACTIVITY | |
| SENSITIVITY | Endogenous |
| MW (kDa) | 49 |
| SOURCE | Rabbit |
Product Information
Storage
Specificity / Sensitivity
Source / Purification
Background
Caspase-9 is phosphorylated at Thr125 through the p44/42 MAPK pathway, and this phosphorylation is associated with inhibition of caspase activation (6).
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- Srinivasula, S. M. et al. (1996) J. Biol. Chem. 271, 27099-27106.
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- Li, P. et al. (1997) Cell 91, 479-489.
- Zou, H. et al. (1999) J. Biol. Chem. 274, 11549-11556.
- Srinivasula, S.M. et al. (1998) Mol Cell 1, 949-57.
- Deveraux, Q. L. et al. (1998) EMBO J. 17, 2215-2223.
- Slee, E. A. et al. (1999) J. Cell Biol. 144, 281-292.
- Sun, X.M. et al. (1999) J Biol Chem 274, 5053-60.
- MacFarlane, M. et al. (1997) J. Cell Biol. 137, 469-479.
- Ajimura, M. et al. (1993) Genetics 133, 51-66.
Alternate Names
APAF-3; APAF3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP-9; CASP9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; Caspase-9; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1, regulatory subunit 56
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