Phospho-PANK4 (Thr406) (F5C5H) Rabbit Monoclonal Antibody #59829
- WB
Product Specifications
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 82 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Studies show that PI3K/Akt signaling induces de novo CoA biosynthesis. CoA is a key metabolic cofactor in many metabolic processes, including the tricarboxylic acid (TCA) cycle and fatty acid metabolism, and is synthesized from pantothenate, cysteine, and ATP. Phosphorylation of PANK4 at Thr406 by Akt decreases the suppression of CoA synthesis by PANK4 (5).
Alternate Names
4'-phosphopantetheine phosphatase; DKFZp547M242; FLJ10782; hPanK4; Inactive pantothenic acid kinase 4; PANK4; Pantothenate kinase 4; pantothenate kinase 4 (inactive); Pantothenic acid kinase 4
Limited Uses
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