Phospho-TDP43 (Ser409/Ser410) (F9S3F) Rabbit Monoclonal Antibody #77613
- WB
- IHC
Product Specifications
| REACTIVITY | H M |
| SENSITIVITY | Endogenous |
| MW (kDa) | 48 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IHC-Immunohistochemistry
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunohistochemistry (Paraffin) | 1:800 - 1:3200 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Phosphorylation of full-length and carboxy-terminal fragments of TDP43 at Ser409/Ser410 is a hallmark of TDP43 proteinopathies (6,7).
- Ou, S.H. et al. (1995) J Virol 69, 3584-96.
- Winton, M.J. et al. (2008) J Biol Chem 283, 13302-9.
- Neumann, M. et al. (2006) Science 314, 130-3.
- Cairns, N.J. et al. (2007) Am J Pathol 171, 227-40.
- Buratti, E. and Baralle, F.E. (2001) J Biol Chem 276, 36337-43.
- Neumann, M. et al. (2009) Acta Neuropathol 117, 137-49.
- Cimini, S. et al. (2022) Int J Mol Sci 23, 13753. doi: 10.3390/ijms232213753.
Alternate Names
ALS10; TADBP; TAR DNA binding protein; TAR DNA-binding protein 43; TAR DNA-binding protein-43; TARDBP; TDP-43; TDP43
Limited Uses
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