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PPID (E7Y8I) Rabbit Monoclonal Antibody #78247

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  • WB
  • IP

    Product Specifications

    REACTIVITY H M R
    SENSITIVITY Endogenous
    MW (kDa) 42
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:100

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    PPID (E7Y8I) Rabbit Monoclonal Antibody recognizes endogenous levels of total PPID protein.

    Species Reactivity:

    Human, Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human PPID protein.

    Background

    Peptidyl-prolyl cis-trans isomerase D (PPID) is a ubiquitously expressed cytoplasmic enzyme that catalyzes the cis-trans isomerization of proline imidic bonds within HSP90 complexes to facilitate folding of protein clients, such as steroid hormone receptors (1,2). Research studies have also demonstrated that PPID plays a role in regulating the assembly and release of viruses, such as HCV and SARS-CoV-2 (3,4).

    Alternate Names

    40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; CYP-40; CYP40; CYPD; MGC33096; Peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; PPIase D; PPID; Rotamase D; testicular tissue protein Li 147

    For Research Use Only. Not for Use in Diagnostic Procedures.
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