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PTPRCAP Antibody #68023

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  • WB

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 35
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    PTPRCAP Antibody recognizes endogenous levels of total PTPRCAP protein.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro140 of human PTPRCAP protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Background

    Protein tyrosine phosphatase receptor type C-associated protein (PTPRCAP/LPAP) is a transmembrane adaptor protein in which expression is restricted to cells of the T- and B-lineages (1). Research studies have demonstrated that PTPRCAP undergoes tyrosine phosphorylation in response to T cell activation and is a positive regulator of T cell function (2-4).

    Alternate Names

    CD45 associated protein; CD45-AP; CD45-associated protein; LPAP; Lymphocyte phosphatase-associated phosphoprotein; MGC138602; MGC138603; protein tyrosine phosphatase receptor type C associated protein; Protein tyrosine phosphatase receptor type C-associated protein; protein tyrosine phosphatase, receptor type, c polypeptide-associated protein; protein tyrosine phosphatase, receptor type, C-associated protein; PTCA; PTPRC-associated protein; PTPRCAP

    For Research Use Only. Not for Use in Diagnostic Procedures.
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