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RAIG1 Antibody #5657

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  • WB
  • IF

    Product Specifications

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 40-50
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    • IF-Immunofluorescence 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunofluorescence (Immunocytochemistry) 1:200

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    RAIG1 Antibody recognizes endogenous levels of total RAIG1 protein.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val295 of human RAIG1 protein. Antibodies are purified by protein A and peptide affinity chromatography.

    Background

    Retinoic Acid-Induced Gene 1 (RAIG1), also called RAI3 and GPRC5A, belongs to the family of G protein-coupled receptors (GPCRs). GPCRs are the largest and most abundant receptor family in mammals, composed of more than one thousand members (1). Retinoic acids (RA) are a group of pleiotropic signaling molecules that regulate a broad range of physiologic and developmental processes. It is thought that RAIG1 may be a downstream target of RA signaling (2). RAIG1 is expressed in lung tissue and in several lung cancer cell lines, and encodes a seven-transmembrane glycoprotein presumed to be a lung tumor suppressor gene (3,4).

    Alternate Names

    G protein-coupled receptor class C group 5 member A; G protein-coupled receptor, family C, group 5, member A; G-protein coupled receptor family C group 5 member A; GPCR5A; GPRC5A; Orphan G-protein-coupling receptor PEIG-1; PEIG-1; Phorbol ester induced gene 1; phorbol ester induced protein-1; RAI3; RAIG-1; RAIG1; retinoic acid induced 3; retinoic acid responsive; Retinoic acid-induced gene 1 protein; Retinoic acid-induced protein 3; TIG1; TPA induced gene 1

    For Research Use Only. Not for Use in Diagnostic Procedures.
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