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Ribosomal Protein L26 Antibody

Ribosomal Protein L26 Antibody #2065

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Supporting Data

REACTIVITY	H M R Mk
SENSITIVITY	Endogenous
MW (kDa)	17
SOURCE	Rabbit

Application Key:

WB-Western Blotting

Species Cross-Reactivity Key:

H-Human
M-Mouse
R-Rat
Mk-Monkey

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

Ribosomal Protein L26 Antibody detects endogenous levels of total ribosomal protein L26.

Species Reactivity:

Human, Mouse, Rat, Monkey

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human ribosomal protein L26. Antibodies are purified by protein A and peptide affinity chromatography.

Background

Ribosomal protein L26 (RPL26) is a component of the 60S ribosomal subunit and is involved in translation (1,2). It was shown that RPL26 increases the translation of p53 mRNA by binding to its 5' untranslated region (UTR) after DNA damage. Studies found that overexpression of RPL26 enhances the binding of p53 mRNA to the ribosomes and increases p53 translation. Overexpression of RPL26 also induces cell-cycle arrest at G1 phase and increases radiation-stimulated apoptosis (2).

Database Links

UniProt ID: P61254

Entrez-Gene Id: 6154

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For Research Use Only. Not For Use In Diagnostic Procedures.

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