| Cat. # | Size | Qty. | Price |
|---|---|---|---|
| 30420S | 1 Kit |
|
| REACTIVITY | H Mk |
| Product Includes | Quantity | Isotype | |||
|---|---|---|---|---|---|
| Ki-67 (D3B5) Rabbit mAb (BSA and Azide Free) 34330 | 100 µg | Rabbit IgG | |||
| Ki-67 (8D5) Mouse mAb (BSA and Azide Free) 62548 | 100 µg | Mouse IgG1 |
Product Information
Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein (1) that is universally expressed among proliferating cells and absent in quiescent cells (2). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival (3). Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases (4).
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