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12219
PTMScan® Trypsin Digested Control Peptides I

PTMScan® Trypsin Digested Control Peptides I #12219

The PTMScan® Trypsin Digested Control Peptides I are produced from mouse liver tissue that has been lysed, reduced and alkylated, digested with trypsin, purified, and lyophilized. This is intended to be used as a control for PTMScan® kits. It should not be used for phosphorylated motifs that contain lysine or arginine residues within the context of the antibody motif.

PTMScan® Technology employs a proprietary methodology from Cell Signaling Technology (CST) for peptide enrichment by immunoprecipitation using a specific bead-conjugated antibody in conjunction with liquid chromatography (LC) tandem mass spectrometry (MS/MS) for quantitative profiling of post-translational modification (PTM) sites in cellular proteins. These include phosphorylation (PhosphoScan®), ubiquitination (UbiScan®), acetylation (AcetylScan®), and methylation (MethylScan®), among others. PTMScan® Technology enables researchers to isolate, identify, and quantitate large numbers of post-translationally modified cellular peptides with a high degree of specificity and sensitivity, providing a global overview of PTMs in cell and tissue samples without preconceived biases about where these modified sites occur (1).

  1. Rush, J. et al. (2005) Nat Biotechnol 23, 94-101.
For Research Use Only. Not For Use In Diagnostic Procedures.

AcetylScan is a trademark of Cell Signaling Technology, Inc.
Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
MethylScan is a trademark of Cell Signaling Technology, Inc.
PhosphoScan is a trademark of Cell Signaling Technology, Inc.
PTMScan is a trademark of Cell Signaling Technology, Inc.
UbiScan is a trademark of Cell Signaling Technology, Inc.