Can I use mixed species samples for a PTMScan® experiment?

The PTMScan® technology is compatible with samples derived from all kingdoms of life as well as samples containing mixed species like xenografts (mouse and human), microbiome samples (bacterial and host species), and cells or tissue infected with pathogens. The only requirements are that the genome of the organisms be sequenced and the predicted open reading frames for the expressed proteins from the species under investigation be in the FASTA file format. This allows the search engine(s) performing peptide identification to match the experimentally generated MS2 chromatograms to those predicted by in silico chromatograms.
 

Last updated: September 12, 2024