What types of Immunoglobulins (IgG, IgA, IgM) are expected to increase after SARS-CoV-2 vaccination and what specific antigens are used in the SARS-CoV-2 Spike Protein ELISA kits?

The SARS-CoV-2 Spike Protein Serological IgG ELISA Kit #20154, SARS-CoV-2 Spike Protein Serological IgM ELISA Kit #37322, and SARS-CoV-2 Spike Protein Serological IgA ELISA Kit #58873 use a trimeric, cleavage-resistant SARS-CoV-2 spike protein ectodomain as the antigen.
The SARS-CoV-2 Spike Protein Multi-Domain (S1-NTD, RBD, S1, S2) Serological IgG ELISA Kit #88005 uses 4 different regions of the SARS-CoV-2 spike protein as the antigens in separate wells, as indicated in the product's description (S1-NTD, RBD, S1, and S2).
The SARS-CoV-2 Spike RBD-ACE2 Blocking Antibody Detection ELISA Kit #69486 looks for antibodies present in the sample that block the interaction between the SARS-CoV-2 RBD region (AA 318-541) and human ACE2 (AA 18-615).

Last updated: February 26, 2024