PANK4 Antibodies

Target Information

Plays a role in the physiological regulation of the intracellular CoA concentration. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'-phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. In the C-terminal section; belongs to the damage-control phosphatase family. Phosphopantetheine phosphatase II subfamily. Ubiquitously expressed with higher expression in the muscle. Note: This description may include information from UniProtKB.

Alternate Names