XRCC4 Antibodies
Target Information
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. Belongs to the XRCC4 family. Widely expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Alternate Names
DNA repair protein XRCC4; SSMED; X-ray repair complementing defective repair in Chinese hamster cells 4; X-ray repair cross complementing 4; X-ray repair cross complementing protein 4; X-ray repair cross-complementing protein 4; X-ray repair, complementing defective, repair in Chinese hamster; XRCC4XRCC4 Antibody Products
2 ProductsWhy CST
Cell Signaling Technology is trusted by the global scientific research community. Our highly cited antibodies offer unrivaled specificity and reproducibility. Learn more about why researchers choose CST:
Contact
Don’t see an antibody for your specific needs? Browse more products, learn more about our services or get in touch with us: