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Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.
Expert-reviewed interactive pathway providing a current overview of Hedgehog Signaling.
Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today that it has introduced a highly specific PD-L1 rabbit monoclonal antibody (mAb).
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
Cell Signaling Technology, a leading provider of antibodies, kits and services, announced today that it has won two Life Science Industry Awards® for "Best Antibodies" and "Most Useful Website."
Dako and Cell Signaling Technology (CST) today announced that they have entered into a strategic partnership to supply antibodies for use in Dako-branded companion diagnostics products.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Cell Signaling Technology, Inc. (CST) is ISO 9001:2008 certified for the design, development, and production of monoclonal antibodies (mAbs).
New antibodies for Alzheimer's research were presented at SfN 2022, including tools to study neuroinflammation in glial cells like microglia and astrocytes
Neurodegeneration refers to disorders of the CNS that lead to loss of neurons or glia, and is associated with age-related diseases, autoimmune attacks on the nervous system, or genetic mutations that affect the heath of CNS cells.
We have no specific tips for using FACS-isolated cells in CUT&RUN experiments. Like a cultured cell suspension, if your isolated cells are in less than 40ul PBS, you can move directly to Concanavalin A bead binding by adding wash buffer for a total of 100ul per reaction. Otherwise, you need to either spin the cells and remove some of the PBS or add wash buffer and Concanavalin A beads proportionally based on the volume of PBS you have in your sorted cell sample. In our experience, the Concanavalin A beads do not bind to cells in the pure PBS environment.
Expert-reviewed interactive diagrams providing current overviews of neuronal and glial cell markers, as well as links to products from CST.
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
This guide includes some of the most common markers used to detect neuronal and glial cells, which include oligodendrocytes, astrocytes, and microglia.
Expert-reviewed interactive neuroscience pathways providing current overviews of Parkinson's and Alzheimer's Disease signaling, as well as links to products from CST.
Neurodegeneration is marked by the progressive loss of neuronal function and structure, leading to cognitive disabilities such as dementia.
Proteomics can help elucidate mitochondrial homeostasis and dysfunction, inflammasome activation, and the role of parkin in Parkinson's disease.
Expert-reviewed interactive pathway providing a current overview of the Warburg Effect.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.