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Identification of ALK and ROS1 fusion proteins in non-small cell lung cancer (NSCLC) at Cell Signaling Technology.
Jan 2013, CST granted patent for PCR Methods for detection of a subset of treatable non-small cell lung cancers.
July 2013, CST awarded patents critical to lung cancer therapy. Secures dominant IP position for EML4-ALK in NSCLC that spans from research through diagnosis and therapy.
July 2011, CST granted Patent License to Pfizer under the patent estates pooled by CST and Astellas Pharma, Inc. (Patent Estates) relating to EML4 anaplastic lymphoma kinase (ALK).
PTMScan Discovery in Translational Research (A Case Study)
Jan 2012, Ventana to collaborate with Pfizer & CST on companion diagnostic to identify lung cancer patients with ALK gene rearrangements.
Cell Signaling Technology, Inc. Announces License in Personalized Cancer Diagnostics.
Mass spectrometry-based proteomic methods like PTMScan can be applied in translational research. For example to identify novel biomarkers of disease
Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.
PTMScan Technology enables biomarker discovery and signaling regulation by combining enrichment of post-translational modifications with mass spectrometry.
Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today that it has introduced a highly specific PD-L1 rabbit monoclonal antibody (mAb).
Cell Signaling Technology, Inc. Announces Introduction of Antibody Important to Breast Cancer Research.
Cancer signaling pathways and research resources, including activation state antibodies and proteomic tools to discover post-translational modifications
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
General Manager of Cell Signaling Technology China, Jay Dong, is Elected Co-President of Chinese Society for Cell Biology’s Academia-Industry Consortium for Innovation and Entrepreneurship.
Immunohistochemistry Protocol (Paraffin): easy to follow directions describing the step by step experimental procedure.
Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
CST Media Room
A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.
Learn more about commonly used chemical modulators to study cellular physiology and biology.
Immunohistochemistry is a method for studying antigen localization in tissue sections using antibodies. Learn sample preparation, labeling, & visualization.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Scientific posters presented by CST scientists at various conferences and trade shows through the years.
A scientific resource for the MH2 protein domain containing information on structure, function, and domain binding to phospho-serine motifs during TGF-beta signaling.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling.
Expert-reviewed diagram providing a current overview of the m6A RNA pathway with references to its role in tumor development