Basket Updated
0
Items added
Overview of Adhesion and Extracellular Matrix signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Explore the intricate Wnt Beta Catenin pathway & its role in cell development and disease. Learn more about the signaling cascade of this crucial pathway.
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
Expert-reviewed signaling pathway providing a current overview of adherens junction dynamics and links to products by Cell Signaling Technology.
CST offers a growing portfolio of products for the study of immune checkpoint targets in cancer, including several receptor-ligand pairs.
This interactive guide shows the key cell and functional state markers for tumor-infiltrating immune cells in humans.Web Location: Immunology and Inflammation
The D8L9T CD36 clone from CST (# 14347) exhibits superior sensitivity and specificity by IHC and Western blot when compared to a CD36 clone from an alternative vendor.
Products and Related Resources for Adaptive Immune Response SARS-CoV-2 Research
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
Our Fc Block CD16/CD32 (2.4G2) Rat mAb #88280 binds to the Fc receptor on the surface of live cells and blocks the interaction of the Fc receptor with the Fc domain of antibodies. Preventing this interaction ensures that your antibodies will bind only to their intended target, rather than being sequestered by Fc receptors.
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.
A scientific resource for the ANK protein domain containing information on structure, function, and binding partners.
Products and Related Resources for Fibrosis SARS-CoV-2 Research
It is difficult to predict when the Fc receptor blocking step is necessary, due to the variable interaction of host species with different antibody isotypes and the interference caused by fluorescent dyes directly conjugated to the antibody Fc domain. The presence of these dyes is often sufficient to disrupt Fc receptor binding. If you are unable to conduct an experiment to assess nonspecific binding, we recommend using the CD16/CD32 (2.4G2) Rat mAb #88280 to prevent any unintended antibody binding to the Fc receptor.
Interact with this signaling pathway showing immune checkpoint regulation in the tumor microenvironment, including targets such as PD-L1, GITR, TIM-3, CTLA-4, OX40, and more.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Why not take advantage of our own immune system and the best of its weaponry, the T-cells, to fight cancer? This is the basis of immunotherapy.
Researchers are still working hard to develop effective treatments for SARS-CoV-2 and COVID-19.
This interactive guide shows the most important cell and functional state markers for tumor-infiltrating immune cells in mice.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein modification sites.
Interested in studying senescence? Understanding cell cycle arrest is critical to many fields of research, including development, aging, and cancer.
Explore the complex inflammation signaling pathways. Click here to learn more and understand the molecular basis of inflammation.
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G1/S Checkpoint Signaling.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
Metabolic processes regulate immune cell function in a process known as immunometabolism, which can be studied using these macrophage and T-cell markers.
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
