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Products and Related Resources for Adaptive Immune Response SARS-CoV-2 Research
A scientific resource for the TRAF protein domain containing information on structure, function, and domain binding in TNFR Signaling.
Activation of signaling networks downstream of B-cell receptors leads to altered B-cell phenotypes, which can be identified by cellular markers.
CST offers a growing portfolio of products for the study of immune checkpoint targets in cancer, including several receptor-ligand pairs.
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
Explore the NFkB pathway and its impact on inflammation and immune responses. Click here to learn more about this signaling pathway.
B cells are lymphocytes that are an important part of the humoral immune response. The main role of B cells is to produce antibodies in response to antigens.
Learn about BCR signaling and how it can lead to changes in cell metabolism, gene expression, and cytoskeletal organization. Click here.
Why not take advantage of our own immune system and the best of its weaponry, the T-cells, to fight cancer? This is the basis of immunotherapy.
Interact with this signaling pathway showing immune checkpoint regulation in the tumor microenvironment, including targets such as PD-L1, GITR, TIM-3, CTLA-4, OX40, and more.
Lymphoma is a cancer of the lymphatic system, a key part of the body’s immune system. Treatment options & patient prognoses differ based on lymphoma type.
A scientific resource for the CSD protein domain containing information on structure, function, and domain binding during chromatin remodeling.
Advancements in immunotherapeutics against cancer include receptor agonists, adoptive cell transfer, anti-cancer vaccines, and combination therapies.
For years, the TME could only be viewed in single-cell snapshots by flow cytometry or limited tissue staining. IMC offers a panorama of this dynamic world.
Interact with this CAR-T signaling pathway to learn how the combination of extracellular and intracellular domains, including CD8, CD28, 4-1BB, OX40, or CD27, exert antitumor effects.
Validation for flow cytometry antibodies from CST Cell Signaling Technology
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
Expert-reviewed interactive diagram of Rheumatoid Arthritis Pathogenesis and relevant antibodies for studying targets associated with the autoimmune disease.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST.
This guide includes some of the most common markers used to detect neuronal and glial cells, which include oligodendrocytes, astrocytes, and microglia.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Overview of epigenetic and chromatin regulation pathways, antibodies and related reagents, interactive pathway diagrams, and technical resources for epigenetics research.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
Expert-reviewed interactive diagrams providing current overviews of neuronal and glial cell markers, as well as links to products from CST.