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The Jak/Stat Utilization Table displays the combinatorial use of tyrosine kinases and Stat proteins in cytokine/growth factor signaling.
Jak and cytokine receptor mutations found in various cancers, along with the corresponding PubMed reference(s).
Study the IL-6 pathway and its impact on inflammation and immune regulation. Delve into the intricacies of this signaling cascade. Click here.
Products and Related Resources for Cytokines and Inflammation SARS-CoV-2 Research
Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.
Case Study 3: Exceptional Reproducibility of XP Monoclonal Antibodies from Cell Signaling Technology.
MEDx and CST announce expansion of their ongoing partnership for companion diagnostic (CDx) development using CST® antibodies to meet growing demand in China.
Products and Related Resources for Type I Interferon and Viral Restriction Factors SARS-CoV-2 Research
Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Find Pathways and Diagrams By Disease Area
Expert-reviewed interactive pathway providing a current overview of Inhibition of Apoptosis Signaling.
Resources include signaling pathways, antibodies and companion products, research overviews, technical resources, and recent review articles.
Expert-reviewed interactive diagram of Rheumatoid Arthritis Pathogenesis and relevant antibodies for studying targets associated with the autoimmune disease.
Cell Signaling Technology pathways by research area
Explore the complex inflammation signaling pathways. Click here to learn more and understand the molecular basis of inflammation.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
Identifies and quantifies up to many hundreds of critical signaling nodes across pathways involved in cancer biology, immune cell signaling, and more.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Streamline Targeted Protein Degradation Drug Discovery with specific, application-validated antibodies and industry-leading proteomic services.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
Case Study 4: Exceptional Performance of XP Monoclonal Antibodies from Cell Signaling Technology.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
SignalScan bridges the gap between PCR-based detection of COVID-19 infection and uncovering the molecular signature of infection and host immune response.
There's a need for new methods to diagnose and treat pancreatic cancer. Biomarkers like CA 19-9 and MUC5AC are being explored as prognosis indicators.
The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.
Cancer cells adapt mechanisms to evade death by hijacking mechanisms of immune checkpoint control and modulation of the innate immune response via STING.
Researchers are still working hard to develop effective treatments for SARS-CoV-2 and COVID-19.
